Metametrix Laboratory Testing

Testing Services Overview

Metametrix testing services cover a broad range of metabolic, nutritional, and toxicity profiles. These include organic acids, amino acids, fatty acids, nutrient and toxic elements, vitamins, hormones, cardiovascular risk, bone resorption, and oxidative stress. The Testing Services Overview provides a brief description about each Metametrix testing profile.

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Integrated Profiles Health Risks Profiles Hormones Gastrointestinal Function Immune Function Oxidative Stress Indicators Vitamins Elements Amino Acids Fatty Acids Organic Acids Toxicants and Detoxification
Integrated Profiles		Size	$	Qty
ION Profile Individual Optimal Nutrition (10800)	The ION Profile is a combination of analytes that measure levels of organic acids, amino acids, fatty acids, nutrient and toxic elements, vitamins, and antioxidants. A comprehensive overall health assessment option.The ION Profile is a combination of nutritional analyses that measures levels of organic acids, fatty acids, amino acids, vitamins, minerals, and anti-oxidants. IgG Food, Serum Chemistries, and Neopterin/Biopterin are available as add-ons to the ION. ION Specimen Collection Kit - Blood and Urine (10800) Collection Kit can be used for: 0090* ION Profile - Blood/Urine 0190 ION Profile NY - Blood/Urine 0490* ION Profile w/Amino 40 - Blood/Urine 0590 ION Profile w/Amino 40 NY - Blood/Urine 1075 IgG4 Food Antibodies - Serum 0068* Chemistries - Serum 0088* Neopterin/Biopterin Profile - Urine *Not available in New York Weight: 0.7 lb	ION Profile 0090 ION Profile w/ Amino acids 0490	$743 $817
Cardio/ION Specimen Collection Kit Blood and Urine (11801)	The Cardio/ION Health Profile provides a comprehensive array of parameters to determine overall nutritional status with a specific impact on reducing the risk of cardiovascular disease and improving cardiovascular health. Serum chemistries, IgG Food Antibodies, and the Neopterin/Biopterin profile are also available as add-ons to the Cardio ION. Cardio/ION Specimen Collection Kit - Blood and Urine (1180) Specimen Collection Kit can be used for: 0290 Cardio/ION Profile - Blood/Urine 1075 IgG4 Food Antibodies - Serum 0068 Chemistries - Serum 0088 Neopterin/Biopterin Profile* - Urine *Not available in New York Weight: .75 lb	Cardio/ION 11801	$883
TRIAD Profile Specimen Collection Kit Blood and Urine (19800)	The TRIAD Profile allows simultaneous assessment of food sensitivities and intestinal hyperpermeability; urinary microbial metabolites, detoxification indicators, functional vitamin and mineral sufficiency markers, and neural function markers; and essential amino acid status. The TRIAD Profile also provides the clinician with a powerful array of clinical tools to design appropriate therapeutic interventions for the patient. The Neopterin/Biopterin Profile may also be done as an add-on to the TRIAD. Specimen Collection Kit can be used for: 0400 Triad Profile - Blood/Urine 0088* Neopterin/Biopterin Profile - Urine *Not available in New York Weight: .75 lb	TRIAD Profile 0400 TRIAD Bloodspot 0410	$493 $493
Women's Health Specimen Collection Kit Blood and Urine (5682)	The Women's Health Profile measures organic acids, fatty acids, serum lipid peroxides, ADMA, markers of metabolic syndrome, and estrogen. It can also help assess risk factors associated with genetics, biochemical imbalances, and environmental influences. Specimen Collection Kit can be used for: 4146* Women's Health Profile - Blood/Urine *Not available in New York Weight: .75 lb	Women's Health 5682	$597
Health Risk Profiles		Size	$	Qty
Back to top Bone Resorption Specimen Collection Kit Urine (15800)	The Bone Resorption Assay measures Deoxypyridinoline and pyridinoline which are direct products of the breakdown of bone. By measuring deoxypyridinoline in the urine, our test can help identify accelerated bone breakdown and predict the probability of bone loss without therapy and also help monitor whether therapy is working and measure a patient's response to therapy within three months. Specimen Collection Kit can be used for: 0018 Bone Resorption Weight: 0.45 lb	Bone Resorption Assay 15800	$130
Estronex Specimen Collection Kit – Urine (16800)	The balance of anti- and pro-carcinogenic metabolites of estrogen may be investigated with this profile that measures the 2-, 4-, and 16-alpha-hydroxyderivatives of estrone and the 2- and 4-methoxyestrones. This panel provides comprehensive functional information about phase I and phase II estrogen biotransformation. Certain imbalances in biotransformation have been associated with increased risk of carcinogenesis. If the 2/16 ratio is too low, the use of foods or supplements containing I3C or DIM can stimulate hepatic P450 enzymes to increase the favorable 2-hydroxy derivatives. Improving methylation activity can increase the favorable 2- and 4-methoxyestrones. Specimen Collection Kit can be used for: 0142 Estronex Profile* (0342 NY) 0145 Estronex Profile with Bone Resorption* (0345 NY) (Combined tests 0018 & 0142) *Not available in New York Weight: 0.45 lb	Estronex 0142 Estronex Profile with Bone Resorption* 0145	$177 $237
Cardiovascular Health Risk Specimen Collection Kit - Blood (11800)	The Cardiovascular Health Profile combines both traditional and cutting-edge indicators of cardiovascular health. Risk factors for cardiovascular disease (CVD) that are analyzed include such parameters as cholesterol, lipoproteins, triglycerides, fibrinogen, C-reactive protein, homocysteine, lipid peroxides, vitamin E, magnesium, coenzyme Q10, insulin, total testosterone, free androgen index, sex hormone binding globulin, and ferritin. Specimen Collection Kit can be used for: 0161 Cardiovascular Health Profile Weight: .6 lb	Cardiovascular Health Risk 11800	$371
Metabolic Syndrome Specimen Collection Kit	Metabolic Syndrome is characterized by a group of metabolic risk factors that include: central obesity, dyslipidemia, elevated blood pressure, insulin resistance or glucose intolerance, increased tendency to clot, and inflammation. The Metametrix Metabolic Syndrome Profile compiles several laboratory markers of the metabolic syndrome together, allowing for a more comprehensive evaluation. The cutting-edge marker, ADMA, accentuates the innovative combination of analytes within this profile, allowing clinicians to have an unprecedented view into endothelial function. Specimen Collection Kit can be used for: 0146 Metabolic Syndrome Profile - Plasma/Serum Not available in New York Weight: 0.5 lb	Metabolic Syndrome Profile 0146	$228
ADMA Specimen Collection Kit - Plasma (14800)	Asymmetric Dimethylarginine (ADMA) is the principal endogenous inhibitor of nitric oxide synthase. Elevated ADMA is a risk factor for hypertension, cardiovascular disease, renal failure, and erectile dysfunction. Two factors that contribute to elevated ADMA are increased oxidative challenge and folic acid insufficiency. Specimen Collection Kit can be used for: 0014* ADMA (Asymmetric Dimethlarginine) *Not available in New York Weight: 0.45 lb	ADMA Health Risk 11800	$173
Hormones		Size	$	Qty
Back to top Adrenal Stress Specimen Collection Kit - Saliva (51800)	The procedure monitors the circadian variation of the cortisol and DHEA-S levels. An increased cortisol level, a decreased DHEA-S level, or a decrease in the DHEA-S/cortisol ratio is an indication of a stressful physical or mental condition. When the adrenal stress profile indicates an inappropriate hormonal stress response, it is necessary to consider stress reduction along with diet, exercise, and nutritional supplementation to support adrenal gland activity. Specimen Collection Kit can be used for: 0043* Adrenal Stress Plus 0243* Adrenal Stress *Not available in New York Weight: 0.35 lb	Adrenal Stress Profile 0043 Adrenal Stress Profile Plus sIgA & Antigliadin Antibody 0243	$135 $189
Hormones Specimen Collection Kit - Serum (50800)	Male hormones are tested to ensure balance and metabolism. Insulin testing also included in this kit measures serum levels of IGF-1 or serum insulin assessment. Specimen Collection Kit can be used for: 0044 Insulin - Serum 0045 Insulin-Like Growth Factor Type 1 - (IGF-1) 0140 Male Hormone Profile - Serum Weight: 0.5 lb	Insulin 0044 IGF-1 0045 Male Hormone Profile 0140	$81 $99 $134
Gastrointestinal Function		Size	$	Qty
Back to top GI Effects Specimen Collection Kit - Stool (71860)	GI Effects Profiles uses DNA analysis to identify microbiota - including anaerobes, a previously immeasurable area of the gut environment. In addition to much more comprehensive bacteriology, mycology, and parasitology, GI Effects Profiles report drug resistance genes, antibiotic and botanical sensitivities, gliadin-specific sIgA, Elastase1, plus other inflammation, digestion, and absorption markers clinicians requested. Specimen Collection Kit can be used for: 2200* GI EffectsSM Comprehensive Profile (inc. 2205, 2120, 2110) * 2105* Microbial Ecology Profile (inc. 2110) * 2110* Mycology Profile 2120* Chemistries Profile *Not available in New York Weight: 0.5 lb	GI Effects Profile 2100* Microbial Ecology Profile 2105* Mycology Profile 2115* Chemistries Profile 2120*	$443 $272 $84 $191
Back to top Additional Add-On Markers for specific stool tests listed above (as specified by parentheses)	GI Effects Profiles uses DNA analysis to identify microbiota - including anaerobes, a previously immeasurable area of the gut environment. In addition to much more comprehensive bacteriology, mycology, and parasitology, GI Effects Profiles report drug resistance genes, antibiotic and botanical sensitivities, gliadin-specific sIgA, Elastase1, plus other inflammation, digestion, and absorption markers clinicians requested. Specimen Collection Kit can be used for: 2130 Campylobacter (GI Effects 2200, 2205) 2131 Clostridium difficile EIA (GI Effects 2200, 2205) 2132 Escherichia coli EIA (GI Effects 2200, 2205) 2133 Helicobacter pylori EIA (GI Effects 2200, 2205) *Not available in New York Weight: 0.5 lb	2130 Campylobacter 2131 Clostridium difficile EIA 2132 Escherichia coli EIA 2133 Helicobacter pylori EIA	$26 $99 $26 $99
Immune Function		Size	$	Qty
Back to top Allergy/Antibody Specimen Collection Kit - Serum (30800)	The Allergix profiles include IgE food and inhalant allergy testing, as well as IgG food sensitivity testing and celiac disease testing. This particular kit may be used for any of these tests or various combinations of tests. Specimen Collection Kit can be used for: 0075 IgG4 Food Antibodies 0077 IgE Food Antibodies 0270 IgG4 & IgE Food Antibodies 0071 IgE Food Antibodies NY 0271 IgG4 & IgE Food Antibodies NY 7200 IgE Inhalant Antibodies 0078 Celiac Profile 0278 IgG4 Food Antibodies & Celiac Profile Weight: 0.4 lb	IgG4 Food Antibodies 0075 IgE Food Antibodies 0077 IgG4 & IgE Food Antibodies 0270 IgE Food Antibodies NY 0071 IgG4 & IgE Food Antibodies NY 0271 IgE Inhalant Antibodies 7200 Celiac Profile 0078 IgG4 Food Antibodies & Celiac Profile 0278	$211 $195 $294 $? $? $367 $129 $291
Bloodspot IgG Food Antibodies Specimen Collection Kit - Bloodspot (30801)	The Bloodspot IgG Food Antibody Assay is a blood spot test that measures the total IgG levels that react to common food antigens. The test kit is simple enough for the patient to use at home. Specimen Collection Kit can be used for: 0076* Bloodspot Food Antibodies *Not available in New York Weight: 0.3 lb	Bloodspot Food Antibodies 0076*	$128
Gliadin Sensitivity Profile This only tests for Alpha-gliadin see Cyrex Lab panel for full Gluten testing	br>The Gliadin Sensitivity Profile offers a simple, salivary collection measuring anti-gliadin antibody (AGA) and secretory immunoglobulin A (sIgA). AGA measures the body's response to gluten while sIgA defends against antigenic and infectious attacks at the mucosal surfaces. Specimen collection kit can be used for: 0072 Gliadin Sensitivity Profile* *Not available in New York Weight: 0.5 lb	Gliadin Sensitivity Profile 0072*	$129
Oxidative Stress Indicators		Size	$	Qty
Back to top Lipid Peroxides Profile - Serum	Lipid peroxides are the products of chemical damage done by oxygen free radicals to the polyunsaturated fatty acids of cell membranes. This test is an assay of total thiobarbituric acid-reactive substances (TBARS) in serum using HPLC. The HPLC separation step isolates the TBARS from potential interfering compounds that can give false elevations in a simple colorimetric assay. The results provide a measure of total serum lipid peroxidation, an indicator of whole body free radical activity. High levels of lipid peroxides are associated with cancer, heart disease, stroke, and aging.	Lipid Peroxides - Serum 0051	$105
*0087 DNA/Oxidative Stress Marker (8-OHdG) - Urine**	The interaction of reactive oxygen species with DNA and RNA produces oxidation products of these base rings. DNA repair enzymes must remove the damaged bases in order to maintain viability. Oxidation of guanosine produces 8-hydroxy-2'-deoxyguanosine (8OHdG). The concentration of 8OHdG in urine has been shown to be an accurate measure of the rate of polynucleotide oxidative damage. Elevated 8OHdG is a sign that antioxidant nutrient intake may need to be increased. Toxicants and lifestyle stress factors may contribute to increased oxidative challenge	DNA/Oxidative Stress Marker (8-OHdG) - Urine 0087*	$117
Vitamins		Size	$	Qty
Back to top Fat-soluble Vitamins Specimen Collection Kit - Serum (68800)	The Fat-Soluble Vitamins Profile is a great tool to gain an overall perspective of a patient - health, nutrient processing, and dietary insufficiencies. Serum levels of the fat-soluble vitamins A, D, E, K plus beta-carotene and coenzyme Q10 are measured to evaluate total body status of these antioxidant nutrients. Specimen Collection Kit can be used for: 0036 Coenzyme Q10/Vitamins A, E, D, K & Beta-Carotene 0033 Coenzyme Q10/Vitamins A, E & Beta-Carotene 0031* Vitamin K Assay 0032 Vitamin D 0034 Coenzyme Q10 (CoQ10) *Not available in New York Weight: 0.5 lb	Coenzyme Q10/Vitamins A, E, D, K & Beta-Carotene 0031* Coenzyme Q10/Vitamins A, E & Beta-Carotene 0033 Vitamin K Assay 0031* Vitamin D 0032 Coenzyme Q10 0034	$237 $195 $113 $110 $117
Elements		Size	$	Qty
Back to top Nutrient/Toxic Elements Specimen Collection Kit - Hair (40800)	Hair is unique in its ability to concentrate divalent cations because of the high amount of sulfur amino acids that act as strong binding sites. Toxic heavy metals and essential trace elements are found in hair in levels many times higher than those found in any other tissue. 24 elements and metals are tested. Specimen Collection Kit can be used for: 0020* Nutrients & Toxic Elements - Hair *Not available in New York Weight: 0.05 lb	Nutrients & Toxic Elements - Hair 0020*	$103
Nutrient and Toxic Elements Specimen Collection 6-8 hours or 24 hours Urine (40805)	In the Metametrix Nutrient & Toxic Elements Profile, the total output of urine over 6-8 hours or 24 hours is collected and the daily output of elements is determined. The test may be used with or without administration of chelating agents to assess the rate of excretion of the elements reported. Specimen Collection Kit can be used for: 0052* Nutrient & Toxic Elements (6-8 hour) - Urine 0055 Nutrient & Toxic Elements (6-8 hour) NY - Urine 0152* Toxic Metals Only (6-8 hour) - Urine 0155 Toxic Metals Only (6-8 hour) NY - Urine 0158 Toxic Metals Only (24 hour) - Urine *Not available in New York Weight: 0.05 lb	Nutrient & Toxic Elements 0052* Nutrient & Toxic Elements NY 0055 Toxic Elements Only 0152* Toxic Elements Only NY 0155 Toxic Metals Only 24 hour 0148	$112 $? $93 $? $93
Amino Acids		Size	$	Qty
Back to top Amino Acids and Fatty Acids Specimen Collection Kit - Plasma (20800)	This kit provides plasma analysis to determine amino acid imbalances, functional vitamin and mineral deficiencies, diagnosis of metabolic disorders. It may also be used for measuring elevated total homocysteine in plasma to assess risk for heart disease and atherothrombotic cerebrovascular disease. Additionally, measure fatty acid levels to monitor response to supplements and dietary modifications, as well as help manage heart disease and other inflammatory processes. Specimen Collection Kit can be used for: 0010 Amino Acids 40 - Plasma 0011 Amino Acids 20 - Plasma 0040 Fatty Acids - Plasma 0093 Homocysteine - Plasma 0240 AA/EPA Ratio - Plasma Weight: 0.45 lb	Amino Acids 40 - Plasma 0010 Amino Acids 20 - Plasma 0011 Fatty Acids - Plasma 0040 Homocysteine - Plasma 0093 AA/EPA Ratio - Plasma 0240	$297 $208 $275 $141 $149
Amino Acids Specimen Collection Kit - Urine (20801)	The urine amino acid profile reports levels of essential amino acids and their derivatives in categories. Functional vitamin and mineral deficiencies and diagnosis of metabolic disorders can be determined from a urine amino acid analysis. Specimen Collection Kit can be used for: 0012 Amino Acids 40 - Urine Weight: 0.5 lb	Amino Acids 40 - Urine 0012	$297
Bloodspot Amino Acids Specimen Collection Kit - Bloodspot (20802)	The Bloodspot Amino Acid Assay is a non-invasive alternative to the blood draw in determining essential amino acid status and therefore may be a better alternative in the pediatric setting. The test kit is simple enough for the patient to use at home. A formula for a custom amino acid blend is provided with every bloodspot amino acid test result. Specimen Collection Kit can be used for: 0013* Bloodspot Amino Acids 11 0113* Bloodspot Amino Acids 20 *Not available in New York Weight: 0.3 lb	Bloodspot Amino Acids 11 0013* Bloodspot Amino Acids 20 0113*	$112 $208
Fatty Acids		Size	$	Qty
Back to top Fatty Acid Specimen Collection Kit - RBC (22800)	This test is preferred to assess nutritional status of the critical eicosanoid and long chain fatty acids necessary for membrane stabilization. The red cell stearic/oleic ratio is also a cancer therapy marker. Specimen Collection Kit can be used for: 0041 Fatty Acids (Plus ratios) Weight: 0.45 lb	Fatty Acids (Plus ratios) 0041	$275
Bloodspot Fatty Acid Specimen Collection Kit - Bloodspot (27800)	This ratio of the principle omega-3 and omega-6 fatty acids is a measure of the body's eicosanoid balance. Balancing the eicosanoids in the body is an excellent way for managing heart disease and other chronic and inflammatory processes. Specimen Collection Kit can be used for: 0241* Bloodspot Fatty Acids *Not available in New York Weight: 0.3 lb	Bloodspot Fatty Acids 0241*	$148
Organic Acids		Size	$	Qty
Back to top Organix Specimen Collection Kit - Urine (23800)	Organix profiles provide a view into the body's cellular metabolic processes and the efficiency of metabolic function. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes. Specimen Collection Kit can be used for: 0091 Organix Comprehensive - Urine 0291 Organix Basic - Urine 0097 Organix Dysbiosis - Urine *Not available in New York Weight: 0.45 lb	Organix Comprehensive - Urine 0091 Organix Basic - Urine 0291 Organix Dysbiosis - Urine 0097	$321 $202 $202
Toxicants and Detoxification		Size	$	Qty
Back to top Porphyrin Specimen Collection Kit - Urine (41800)	The Porphyrins Profile evaluates the biomarkers of toxicity. Patterns of specific porphyrin elevations in urine may serve as functional markers of toxicity from toxic metals, such as mercury, lead, or arsenic, or other organic chemicals. The Neopterin/Biopterin Profile may also be done as an add-on to the Porphyrins Profile. Specimen Collection Kit can be used for: 0060* Porphyrins Profile 0088* Neopterin/Biopterin Profile *Not available in New York Weight: 1.7 lb	Porphyrins Profile 0060* Neopterin/Biopterin Profile 0088*	$172 $112
Toxic Effect Profiles - PCBs, Chlorinated Pesticides, and Volatile Solvents	The PCBs and Chlorinated Pesticides Profiles measure for common PCBs and chlorinated pesticides shown to cause health problems. Both PCBs and chlorinated pesticides are stored in fatty tissue and bioaccumulate over a patient's lifetime. Symptoms of PCB exposure may include psychomotor and behavioral problems, allergies, obesity, fatigue, and even some cancers. Chlorinated pesticides can cause a range of illnesses from allergies and asthma to cardiovascular disease and cancer. Volatile solvents may cause symptoms ranging from blood disorders to muscular weakness and atophy. These toxins may also be the underlying cause of many illnesses such as diabetes, fibromyalgia, brain fog, and mood disorders, to name a few. The Volatile Solvents Profile measures exposure to common volatile solvents in our working and living environments. Determining a patient's exposure to these environmental toxins can assist with treatment planning to help achieve patient wellness. Specimen Collection Kit can be used for: 0760* Chlorinated Pesticides Profile 0761* Polychlorinated Biphenyls (PCBs) Profile 0762* Volatile Solvents Profile *Not available in New York Weight: 0.3 lb	Chlorinated Pesticides Profile 0760* Polychlorinated Biphenyls (PCBs) Profile 0761* Volatile Solvents Profile 0762*	$220 $220 $292
Phthalates & Parabens Profile	The Phthalates & Parabens Profile helps assess levels of phthalates and parabens in the body, which can help identify if exposures correlate with health issues. Phthalates and parabens are known as xenoestrogens, which bind to estrogen receptors and disrupt the endocrine system. Knowing a patient's body burden of phthalates and parabens can assist in creating treatment plans to help achieve patient wellness. Specimen Collection Kit can be used for: 0740* Phthalates & Parabens Profile *Not available in New York Weight: 0.3 lb	Phthalates & Parabens Profile 0740*	$232

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